Nchekwa PRP na ntụkwasị obi

Kedu ka PRP si bụrụ ntụkwasị obi?

PRP na-eme site na mbelata nke mkpụrụ irighiri alfa na platelet, nke nwere ụfọdụ ihe na-eto eto.A ga-akwadorịrị PRP na steeti anticoagulant na a ga-eji ya mee ihe na grafts, flaps, ma ọ bụ ọnya n'ime nkeji 10 nke mmalite clot.

Dị ka platelet na-arụ ọrụ site na usoro mkpụkọ, a na-ezobe ihe ndị na-eto eto site na cell site na akpụkpọ ahụ cell.N'ime usoro a, mkpụrụ irighiri alfa na-ejikọta membranes cell platelet, na ihe ndị na-eto eto protein na-emecha ọnọdụ bioactive site n'itinye ụdọ histone na carbohydrate na protein ndị a.

Nnyocha egosiwo na ndị okenye mmadụ mesenchymal stem cell, osteoblasts, fibroblasts, endothelial cell, na epidermal cell na-egosipụta ndị na-anabata akpụkpọ anụ cell maka ihe ndị na-eto eto na PRP.Ndị na-anabata transmembrane ndị a na-eme ka ndị na-emepụta ihe na-eme ka ndị na-edozi ahụ pụta ìhè na-eduga na nkwupụta (mkpọghe) nke usoro mkpụrụ ndụ cell nkịtị, dị ka mmụba cell, nhazi nke matrix, nhazi osteoid, collagen synthesis, wdg.

Ya mere, ihe ndị na-eto eto PRP adịghị abanye na cell ma ọ bụ nucleus, ha abụghị mutagenic, ha na-eme ka mkpali nke ọgwụgwọ nkịtị dị ngwa ngwa.

Mgbe mmalite mmalite nke ihe uto metụtara PRP, platelet na-emepụta ma zoo ihe ndị ọzọ na-eto eto maka ụbọchị 7 fọdụrụ nke ndụ ha.Ozugbo platelet agwụla ma nwụọ, macrophages na-erute mpaghara ahụ site na arịa ọbara na-akpali akpali na-etolite n'ime iji rụọ ọrụ nke onye na-ahụ maka ọgwụgwọ ọnya site na izopụta ụfọdụ ihe na-eto eto yana ndị ọzọ.Ya mere, ọnụ ọgụgụ platelet dị na aka aka, ọnya, ma ọ bụ mkpụkọ ọbara nke etinyere na flap na-ekpebi ka ọnya ahụ na-adị ngwa ngwa.PRP na-agbakwunye na nọmba ahụ.

1) PRP nwere ike ịkwalite mkpụrụ ndụ progenitor ọkpụkpụ n'ime ọkpụkpụ na ọkpụkpụ na-akwado ma kwalite ọkpụkpụ ọkpụkpụ.PRP nwekwara ihe dị iche iche na-eto eto, nke nwere ike ịkwalite nkewa cell na ọdịiche dị iche iche ma kwalite nrụzi ahụ.

2) Leukocytes na PRP nwere ike ịkwalite ikike mgbochi ọrịa nke saịtị ahụ merụrụ ahụ, na-enyere ahụ aka iwepụ anụ ahụ necrotic, ma mee ngwa ngwa nrụzi mmerụ ahụ.

3) PRP nwere nnukwu fibrin, nke nwere ike wulite ikpo okwu nrụzi ka mma maka nrụzi ahụ ma belata ọnya n'otu oge.

PRP ọ dị mma ma dị irè?

1) Ngwaahịa ọbara akpaaka

Ọnụ ọgụgụ dị ukwuu nke data nyocha egosila na PRP nwere ike igosipụta nchekwa ya na ntụkwasị obi ya n'ọtụtụ ọgwụgwọ.Dị ka ngwaahịa ọbara autologous, PRP na-ezere nke ọma ịjụ na mgbasa ọrịa nke sitere na ntinye nke ọbara allogeneic n'oge ọgwụgwọ.

2) Onye mmalite coagulation adịghị mma

PRP na-eji thrombin bovine dị ka onye mbido coagulation, na-eme ka mmịpụta PRP n'otu oge na usoro ịwa ahụ.A na-edozi thrombin anụ ahụ nke a na-eji eme ihe na-ekpo ọkụ ma ọ dịghị ebute ọrịa.Na n'ihi na ọnụọgụ thrombin bovine ejiri dị ntakịrị, ọ naghị abanye n'ime ahụ ma mee ka a jụrụ ya n'oge eji.

3) Ngwaahịa dị mma ma dị irè

A na-eji usoro Aseptic eme ihe na nkwadebe PRP, na-ebute mkpụkọ ọbara nke na-adịghị akpata nsogbu ọrịa na-adịghị ebute nje bacteria.

(A na-ebipụtaghachi ọdịnaya nke isiokwu a, ma anyị anaghị enye nkwa ọ bụla ma ọ bụ nkwenye doro anya maka izi ezi, ntụkwasị obi ma ọ bụ izu oke nke ọdịnaya dị n'ime edemede a, ọ bụghịkwa maka echiche nke isiokwu a, biko ghọta.)